Recent publications from Centre members:
Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas
Science Translational Medicine. 2021 October
Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome
Nature Communications. 2021 February
Clinical Outcomes and Patient-Matched Molecular Composition of Relapsed Medulloblastoma
Journal of Clinical Oncology. 2021 January
Journal of Clinical Investigation. 2020 November
DDX3X Suppresses the Susceptibility of Hindbrain Lineages to Medulloblastoma
Developmental Cell. 2020 July
Tumor Necrosis Factor Overcomes Immune Evasion in p53-mutant Medulloblastoma
Nature Neuroscience. 2020 May
Germline Elongator mutations in Sonic Hedgehog medulloblastoma
Nature. 2020 April
Public resources for chemical probes: the journey so far and the road ahead.
Future Medicinal Chemistry. 2019 November
Recurrent non-coding U1-snRNA mutations drive cryptic splicing in Shh medulloblastoma.
Nature. 2019 October
DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome.
Nature. 2019 September
Nature Comms. 2019 September
Reply to ‘Assembling the brain trust: the multidisciplinary imperative in neuro-oncology’.
Nat Rev Clin Oncol 2019 August
Challenges to curing primary brain tumours.
Nat Rev Clin Oncol 2019 August
Cancer Chemother Pharmacol 2019 August
Resolving medulloblastoma cellular architecture by single-cell genomics
Nature. 2019 July
Myc and Loss of p53 Cooperate to Drive Formation of Choroid Plexus Carcinoma
Cancer Research. 2019 May
Small-molecule targeting of brachyury transcription factor addiction in chordoma.
Nature Medicine. 2019 February
