Choroid Plexus Carcinoma
Choroid plexus carcinomas (CPC) are aggressive malignant tumours of the central nervous system occurring mainly in young children under the age of 1. Advances in the clinical and molecular stratification for many types of childhood brain tumours have provided a foundation for risk-adapted treatment planning and improvements in outcome. There are numerous barriers to understanding the best treatments strategies in children with CPC. Currently, the outcome of patients remains guarded and treatments have been based on case series and expert opinions, with no established “standard of care”. Work at the Centre is aimed at improving the outcomes for patients with CPC through achieving a deeper understanding of the mechanisms underlying the formation of this disease and through carrying out pre-clinical studies.