Our People

The CRUK Children’s Brain Tumour Centre of Excellence is hosted by the University of Cambridge and the Institute of Cancer Research. The Centre fosters collaborations across the United Kingdom and internationally to form our community

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International Centres

Institute of Cancer Research

The Institute of Cancer Research, London, is one of the world’s most influential cancer research organisations. We are a UK charity and member institution of the University of London.

https://www.icr.ac.uk

CRUK Cambridge Institute

Cancer Research UK Cambridge Institute combines basic and clinical research with innovative technologies..

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SickKids

The Hospital for Sick Children, corporately branded as SickKids, is a major pediatric teaching hospital located on University Avenue in Toronto, Ontario, Canada.

Visit Sickkids website

St Jude Children's Research Hospital

St. Jude is leading the way the world understands, treats and defeats childhood cancer and other life-threatening diseases.

Visit St.Jude Children's Hospital website

Texas Children's Hospital

By doing things differently, we deliver the impossible for the benefit of the world.

Visit Texas Children's website

Stanford Medicine Children’s Health

Stanford Medicine Children’s Health, along with Stanford Health Care and the Stanford School of Medicine, is part of Stanford Medicine. Together, we harness the potential of biomedicine through collaborative research, education, and clinical care. Precision health is at the core of what we do: preventing disease before it strikes and treating it decisively when it does.

Visit Stanford Children's Health Care website

Memorial Sloan Kettering Cancer Centre

Changing how the world treats Cancer through research

Visit the Memorial Sloan Kettering Cancer Centre website

University College London

Founded in 1826 in the heart of London, UCL is London's leading multidisciplinary university, with more than 16,000 staff and 50,000 students from over 150 different countries

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Great Ormond Street Hospital London

Great Ormond Street Hospital (GOSH) is one of the world’s leading children's hospitals.

Visit the Great Ormond Street Hospital for Children

DKFZ Germany (Heidleberg)

German Cancer Research Center

Visit the German Cancer Research Center

Princess Maxima Netherlands

Center of Pediatric Oncology - Providing the best care for children with cancer

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Dana Farber Cancer Institute, Boston

Have led the world by making life-changing breakthroughs in cancer research and patient care, providing the most advanced treatments available.

Visit the Dana Farber website

The Centre of Excellence Team

The Centre is co-directed by Professors Richard Gilbertson (University of Cambridge) and Paul Workman (Institute of Cancer Research).  They had a vision to transform treatments for children with brain tumours through establishing the Centre, with one of the first academic drug discovery groups focused on paediatric brain cancers.

 

Centre Research Groups

Together we have four academic groups in the Institute of Cancer Research, London and three groups working in the University of Cambridge in the fields of pharmacology, medicinal chemistry, biochemistry and paediatric brain tumour model development. Group leaders, PhD students, postdoctoral research fellows, staff scientists and research technicians make up the team across the host institutes.

International collaborators

The Centre has several international collaborators who are clinical researchers and world leaders in paediatric neuro-oncology research working on projects under the Centre umbrella. The New Roads Project for innovative approaches to curing brain tumours is one of our main projects which is lead by Professor Gilbertson and has team members from the UK, USA and Canada. Scroll down below to meet the team!

 

International Children’s Brain Tumour Board

The International Children’s Brain Tumour Board is the collaborative heart of the Centre, aligning the paediatric brain tumour community in order to achieve the Centre’s research strategy and goals. This board ensures the design of preclinical trials and biomarkers that position drugs for rapid clinical translation. The International Children’s Brain Tumour Board includes global experts in paediatric brain tumours, enabling them to input directly into the Centre’s drug discovery and development pipeline. Scroll down below to meet the board members.

Centre Directors

Professor Richard Gilbertson

Theme: Models and therapies for Ependymoma, Choroid Plexus Carcinoma and Medulloblastoma tumours

Affiliation: The Gilbertson Lab, CRUK Cambridge Institute, University of Cambridge

Professor Paul Workman

Theme: Molecular Pharmacology and drug discovery

Affiliation: Institute of Cancer Research

Centre Group Leaders

Professor Richard Gilbertson

Theme: Models and therapies for Ependymoma, Choroid Plexus Carcinoma and Medulloblastoma tumours

Affiliation: The Gilbertson Lab, CRUK Cambridge Institute, University of Cambridge

Professor Paul Workman

Theme: Molecular Pharmacology and drug discovery

Affiliation: Institute of Cancer Research

Dr Gary Newton

Theme: New drugs for treatment of ependymoma

Affiliation: Medicinal Chemistry Team, Institute of Cancer Research

Dr Manav Pathania

Theme: Diffuse Midline Glioma

Affiliation: Pathania Lab, The Milner Institute, University of Cambridge

Professor Chris Jones

Theme: Diffuse Midline Glioma

Affiliation: Jones Group, Institute of Cancer Research

Dr Pau Creixell

Theme: Cancer Signalling and Brain Tumour Therapeutics

Affiliation: The Creixell Lab, CRUK Cambridge Institute, University of Cambridge

Professor Louis Chesler

Theme: Group 3 and Group 4 medulloblastoma

Affiliation: Paediatric Solid Tumour Biology and Therapeutics Team at Institute of Cancer Research

Scientific Manager

Dr Emily Linnane

Theme: Drug discovery

Affiliation: CRUK Cambridge Institute, University of Cambridge

The New Roads Team; Innovative Approaches to Curing Brain Tumours

Professor Paul Lehner

Theme: Identify brain tumour cell dependencies and matched novel therapeutics

Affiliation: University of Cambridge

Country: U.K

Dr Luis F. Parada

Theme: Identify brain tumour cell dependencies and matched novel therapeutics

Affiliation: Memorial Sloan Kettering Cancer Center

Country: USA

Professor Tom Jacques

Theme: Generate molecular and functional atlases of human and mouse brain and their tumours at single cell resolution

Affiliation: Institute of Child Health and University College London

Country: U.K

Professor Darren Hargrave

Theme: Preclinical testing of novel therapies

Affiliation: Institute of Child Health and University College London, Great Ormand Street Hospital

Country: U.K

Dr Peter Dirks

Theme: Generate molecular and functional atlases of human and mouse brain and their tumours at single cell resolution

Affiliation: The Hospital for Sick Children (Sick Kids)

Country: Canada

Dr Michelle Monje

Theme: Generate molecular and functional atlases of human and mouse brain and their tumours at single cell resolution

Affiliation: Stanford University

Country: USA

Professor Richard Gilbertson

Theme: Models and therapies for Ependymoma, Choroid Plexus Carcinoma and Medulloblastoma tumours

Affiliation: The Gilbertson Lab, CRUK Cambridge Institute, University of Cambridge

Dr Michael Taylor

Theme: Identify brain tumour cell dependencies and matched novel therapeutics

Affiliation: Texas Children's Hospital

Country: USA

International Children's Brain Tumour Board



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