Centre Group Leaders
- Professor Louis Chesler and his team and the Institute of Cancer Research works on identifying the cellular origins of paediatric brain tumours; discovering the genetic drivers and cell hierarchies that maintain these tumours.
- Professor Raj Chopra is Head of the Division of Cancer Therapeutics and Director of the CRUK Cancer Therapeutics Unit at the Institute of Cancer Research (ICR). He is an experienced scientist and clinical leader who has discovered and developed novel cancer therapies. He is Head of the Division of Cancer Therapeutics and Director of the Cancer Research UK Cancer Therapeutics Unit, and his group focuses on haematological oncology, solid tumour biology, transplantation and cell therapies.
- Professor Ian Collins is a member of the CRUK Cancer Therapeutics Unit at the ICR. He is an expert medicinal chemist whose team develops molecules to understand cancer biology. His team develops molecules which are then used as tools to understand cancer biology and can be developed to make new drugs.
- Professor Richard Gilbertson is the Director of the CRUK Cambridge Centre and Head of the Department of Oncology at the University of Cambridge. He is a clinician scientist specialising in paediatric neuro-oncology and a world-leader in the biology and treatment of paediatric brain tumours. The principal aim of his lab is to reduce the morbidity and mortality of patients with cancer through improved understanding of tumour biology.
- Professor Chris Jones heads the Glioma Team at the Institute of Cancer Research. The goals of his lab are to identify the genetic and epigenetic drivers of childhood glioma subgroups, and to use derive mechanistic insight in relevant tumour models in order to develop novel therapies for children with these tumours. His team also carries out parallel biology studies alongside international clinical trials in paediatric high grade glioma and DIPG.
- Dr Paul Northcott is an Assistant Member at St Jude Children’s Hospital in Memphis Tennessee, USA. The Northcott Lab aims to fully characterize the molecular, cellular, and biological basis of medulloblastoma, one of the most prevalent types of malignant childhood brain cancer.
- Dr Manav Pathania is a junior group leader in the Centre and in the Department of Oncology at the University of Cambridge. His lab focuses on understanding the role of chromatin remodelling in paediatric brain tumours. The Pathania lab is investigating how epigenetic rewiring support tumour initiation and maintenance and examining if these mechanisms also contribute to the emergence of therapy resistance.
- Professor Stefan Pfister is the Director of the Preclinical Program at the Hopp Children´s Cancer Center at the NCT Heidelberg (KiTZ). His group is interested in investigating the molecular profiles of childhood brain tumours in hopes of developing novel treatments for patients.
- Dr Michael Taylor is a neurosurgeon at Hospital for Sick Children in Toronto, Canada. His lab is interested in the molecular genetics of medulloblastoma and ependymoma, two of the most common malignant paediatric brain tumours. Through a better understanding of the molecular biology of these tumours, they hope to devise novel, more effective treatment strategies.